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Tryptophan scanning of the acetylcholine receptor’s βM4 transmembrane domain: Decoding allosteric linkage at the lipid-protein interface with ion-channel gating

The nicotinic acetylcholine receptor (nAChR) is a ligand-gated ion channel protein that mediates fast excitatory synaptic transmission in the peripheral and central nervous systems. Changes in the structure and function of the AChR can lead to serious impairment of physiological processes. In this s...

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Detalhes bibliográficos
Publicado no:Channels (Austin)
Main Authors: León, Rosedelma Díaz-De, Otero-Cruz, José David, Torres-Nuñez, David Abner, Casiano, Anette, Lasalde-Dominicci, José Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4835820/
https://ncbi.nlm.nih.gov/pubmed/19066450
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