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Tryptophan scanning mutagenesis reveals distortions in the helical structure of the δM4 transmembrane domain of the Torpedo californica nicotinic acetylcholine receptor

The lipid-protein interface is an important domain of the nicotinic acetylcholine receptor (nAChR) that has recently garnered increased relevance. Several studies have made significant advances toward determining the structure and dynamics of the lipid-exposed domains of the nAChR. However, there is...

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Detalhes bibliográficos
Main Authors: Caballero-Rivera, Daniel, Cruz-Nieves, Omar A., Oyola-Cintrón, Jessica, Torres-Núñez, David A., Otero-Cruz, José D., Lasalde-Dominicci, José A.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396688/
https://ncbi.nlm.nih.gov/pubmed/22622285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.19540
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