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Fourier transform coupled to tryptophan-scanning mutagenesis: Lessons from its application to the prediction of secondary structure in the acetylcholine receptor lipid-exposed transmembrane domains

Although Fourier transform (FT) and tryptophan-scanning mutagenesis (TrpScanM) have been extremely useful for predicting secondary structures of membrane proteins, they are deemed to be low-resolution techniques. Herein, we describe the combined use of FT and TrpScanM (FT-TrpScanM) as a more reliabl...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta
Main Authors: Otero-Cruz, José David, Torres-Núñez, David Abner, Báez-Pagán, Carlos Alberto, Lasalde-Dominicci, José Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600069/
https://ncbi.nlm.nih.gov/pubmed/18346473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2008.01.020
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