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Fast and sensitive mapping of nanopore sequencing reads with GraphMap

Realizing the democratic promise of nanopore sequencing requires the development of new bioinformatics approaches to deal with its specific error characteristics. Here we present GraphMap, a mapping algorithm designed to analyse nanopore sequencing reads, which progressively refines candidate alignm...

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Publicat a:Nat Commun
Autors principals: Sović, Ivan, Šikić, Mile, Wilm, Andreas, Fenlon, Shannon Nicole, Chen, Swaine, Nagarajan, Niranjan
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4835549/
https://ncbi.nlm.nih.gov/pubmed/27079541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11307
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