Allele-specific transcription factor binding to common and rare variants associated with disease and gene expression

Genome-wide association studies (GWAS) have identified a large number of disease-associated SNPs, but in few cases the functional variant and the gene it controls have been identified. To systematically identify candidate regulatory variants, we sequenced ENCODE cell lines and used public ChIP-seq d...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Hum Genet
Prif Awduron: Cavalli, Marco, Pan, Gang, Nord, Helena, Wallerman, Ola, Wallén Arzt, Emelie, Berggren, Olof, Elvers, Ingegerd, Eloranta, Maija-Leena, Rönnblom, Lars, Lindblad Toh, Kerstin, Wadelius, Claes
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer Berlin Heidelberg 2016
Pynciau:
Original Investigation
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4835527/
https://ncbi.nlm.nih.gov/pubmed/26993500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-016-1654-x
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