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Allele-specific transcription factor binding to common and rare variants associated with disease and gene expression

Genome-wide association studies (GWAS) have identified a large number of disease-associated SNPs, but in few cases the functional variant and the gene it controls have been identified. To systematically identify candidate regulatory variants, we sequenced ENCODE cell lines and used public ChIP-seq d...

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Publicat a:Hum Genet
Autors principals: Cavalli, Marco, Pan, Gang, Nord, Helena, Wallerman, Ola, Wallén Arzt, Emelie, Berggren, Olof, Elvers, Ingegerd, Eloranta, Maija-Leena, Rönnblom, Lars, Lindblad Toh, Kerstin, Wadelius, Claes
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4835527/
https://ncbi.nlm.nih.gov/pubmed/26993500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-016-1654-x
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