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Looking beyond GWAS: allele-specific transcription factor binding drives the association of GALNT2 to HDL-C plasma levels

BACKGROUND: Plasma levels of high-density lipoprotein cholesterol (HDL-C) have been associated to cardiovascular disease. The high heritability of HDL-C plasma levels has been an incentive for several genome wide association studies (GWASs) which identified, among others, variants in the first intro...

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Publicat a:Lipids Health Dis
Autors principals: Cavalli, Marco, Pan, Gang, Nord, Helena, Wadelius, Claes
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728761/
https://ncbi.nlm.nih.gov/pubmed/26817450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12944-016-0183-x
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