Rapamycin-Induced Hypoxia Inducible Factor 2A Is Essential for Chondrogenic Differentiation of Amniotic Fluid Stem Cells

Amniotic fluid stem (AFS) cells represent a major source of donor cells for cartilage repair. Recently, it became clear that mammalian target of rapamycin (mTOR) inhibition has beneficial effects on cartilage homeostasis, but the effect of mTOR on chondrogenic differentiation is still elusive. There...

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Detalhes bibliográficos
Publicado no:Stem Cells Transl Med
Main Authors: Preitschopf, Andrea, Schörghofer, David, Kinslechner, Katharina, Schütz, Birgit, Zwickl, Hannes, Rosner, Margit, Joó, József Gabor, Nehrer, Stefan, Hengstschläger, Markus, Mikula, Mario
Formato: Artigo
Idioma:Inglês
Publicado em: AlphaMed Press 2016
Assuntos:
Fetal and Neonatal Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4835251/
https://ncbi.nlm.nih.gov/pubmed/27025692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2015-0262
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