Rapamycin-Induced Hypoxia Inducible Factor 2A Is Essential for Chondrogenic Differentiation of Amniotic Fluid Stem Cells

Amniotic fluid stem (AFS) cells represent a major source of donor cells for cartilage repair. Recently, it became clear that mammalian target of rapamycin (mTOR) inhibition has beneficial effects on cartilage homeostasis, but the effect of mTOR on chondrogenic differentiation is still elusive. There...

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Опубликовано в: :Stem Cells Transl Med
Главные авторы: Preitschopf, Andrea, Schörghofer, David, Kinslechner, Katharina, Schütz, Birgit, Zwickl, Hannes, Rosner, Margit, Joó, József Gabor, Nehrer, Stefan, Hengstschläger, Markus, Mikula, Mario
Формат: Artigo
Язык:Inglês
Опубликовано: AlphaMed Press 2016
Предметы:
Fetal and Neonatal Stem Cells
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4835251/
https://ncbi.nlm.nih.gov/pubmed/27025692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2015-0262
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