A carregar...
Deletion of the distal Tnfsf11 RL-D2 enhancer that contributes to PTH-mediated RANKL expression in osteoblast lineage cells results in a high bone mass phenotype in mice
Receptor activator of nuclear factor-κB ligand (RANKL) is a TNF-like cytokine that is necessary for osteoclast formation and survival. Elevated RANKL synthesis is associated with both increased osteoclast number and bone resorption. Earlier studies identified an enhancer 76 kb upstream of the Tnfsf1...
Na minha lista:
| Publicado no: | J Bone Miner Res |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4835217/ https://ncbi.nlm.nih.gov/pubmed/26332516 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2698 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|