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T cell fate and clonality inference from single cell transcriptomes
The enormous sequence diversity within T cell receptor (TCR) repertoires allows specific TCR sequences to be used as lineage markers for T cells that derive from a common progenitor. We have developed a computational method, called TraCeR, to reconstruct full-length, paired TCR sequences from T lymp...
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| Publicado en: | Nat Methods |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4835021/ https://ncbi.nlm.nih.gov/pubmed/26950746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3800 |
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