Coordinate regulation of residual bone marrow function by paracrine trafficking of AML exosomes

We recently demonstrated that acute myeloid leukemia (AML) cell lines and patient-derived blasts release exosomes that carry RNA and protein; following an in vitro transfer, AML exosomes produce proangiogenic changes in bystander cells. We reasoned that paracrine exosome trafficking may have a broad...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Leukemia
Egile Nagusiak: Huan, J, Hornick, NI, Goloviznina, NA, Kamimae- Lanning, AN, David, LL, Wilmarth, PA, Mori, T, Chevillet, JR, Narla, A, Roberts, CT, Loriaux, MM, Chang, BH, Kurre, P
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4834971/
https://ncbi.nlm.nih.gov/pubmed/26108689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2015.163
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