Coordinate regulation of residual bone marrow function by paracrine trafficking of AML exosomes

We recently demonstrated that acute myeloid leukemia (AML) cell lines and patient-derived blasts release exosomes that carry RNA and protein; following an in vitro transfer, AML exosomes produce proangiogenic changes in bystander cells. We reasoned that paracrine exosome trafficking may have a broad...

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Detalhes bibliográficos
Publicado no:Leukemia
Main Authors: Huan, J, Hornick, NI, Goloviznina, NA, Kamimae- Lanning, AN, David, LL, Wilmarth, PA, Mori, T, Chevillet, JR, Narla, A, Roberts, CT, Loriaux, MM, Chang, BH, Kurre, P
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4834971/
https://ncbi.nlm.nih.gov/pubmed/26108689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2015.163
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