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K-Cl cotransporters, cell volume homeostasis, and neurological disease

K(+)-Cl(−) cotransporters (KCCs) were originally characterized as regulators of red blood cell (RBC) volume. Since then, four distinct KCCs have been cloned, and their importance for volume regulation has been demonstrated in other cell types. Genetic models of certain KCCs, such as KCC3, and their...

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Detalhes bibliográficos
Publicado no:Trends Mol Med
Main Authors: Kahle, Kristopher T., Khanna, Arjun R., Alper, Seth L., Adragna, Norma C., Lauf, Peter K., Sun, Dandan, Delpire, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4834970/
https://ncbi.nlm.nih.gov/pubmed/26142773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2015.05.008
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