Loading...
Discovery of Pyrazolopyridones as a Novel Class of Gyrase B Inhibitors Using Structure Guided Design
[Image: see text] The ATPase subunit of DNA gyrase B is an attractive antibacterial target due to high conservation across bacteria and the essential role it plays in DNA replication. A novel class of pyrazolopyridone inhibitors was discovered by optimizing a fragment screening hit scaffold using st...
Na minha lista:
| Udgivet i: | ACS Med Chem Lett |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Chemical
Society
2016
|
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4834655/ https://ncbi.nlm.nih.gov/pubmed/27096044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.5b00368 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|