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Development of a physiologically based pharmacokinetic model of actinomycin D in children with cancer
AIMS: Use of the anti‐tumour antibiotic actinomycin D is associated with development of hepatotoxicity, particularly in young children. A paucity of actinomycin D pharmacokinetic data make it challenging to develop a sound rationale for defining dosing regimens in younger patients. The study aim was...
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| Publicado no: | Br J Clin Pharmacol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4834588/ https://ncbi.nlm.nih.gov/pubmed/26727248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12878 |
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