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MNK1 and MNK2 mediate adverse effects of high-fat feeding in distinct ways

The MAP kinase-interacting kinases (MNK1 and MNK2) are non-essential enzymes which are activated by MAP kinases. They are implicated in controlling protein synthesis. Here we show that mice in which the expression of either MNK1 or MNK2 has been knocked out (KO) are protected against adverse effects...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Moore, C. E. J., Pickford, J., Cagampang, F. R., Stead, R. L., Tian, S., Zhao, X., Tang, X., Byrne, C. D., Proud, C. G.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4834573/
https://ncbi.nlm.nih.gov/pubmed/27087055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23476
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