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The selective sigma-1 receptor antagonist E-52862 attenuates neuropathic pain of different aetiology in rats
E-52862 is a selective σ(1)R antagonist currently undergoing phase II clinical trials for neuropathic pain and represents a potential first-in-class analgesic. Here, we investigated the effect of single and repeated administration of E-52862 on different pain-related behaviours in several neuropathi...
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4834548/ https://ncbi.nlm.nih.gov/pubmed/27087602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24591 |
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