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Effect of hepatic or renal impairment on the pharmacokinetics of evacetrapib

PURPOSE: The aim of this study is to investigate the effect of hepatic or renal impairment on the pharmacokinetics of a single 130-mg evacetrapib dose. METHODS: Two open-label, parallel-design studies in males and females with normal hepatic function or Child-Pugh mild, moderate, or severe hepatic i...

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Bibliografske podrobnosti
izdano v:Eur J Clin Pharmacol
Main Authors: Small, David S., Zhang, Wei, Royalty, Jane, Cannady, Ellen A., Downs, Delyn, Ortega, Demetrio, Suico, Jeffrey G.
Format: Artigo
Jezik:Inglês
Izdano: Springer Berlin Heidelberg 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4834099/
https://ncbi.nlm.nih.gov/pubmed/26857125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00228-016-2017-1
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