Absolute bioavailability of evacetrapib in healthy subjects determined by simultaneous administration of oral evacetrapib and intravenous [(13)C(8)]‐evacetrapib as a tracer

This open‐label, single‐period study in healthy subjects estimated evacetrapib absolute bioavailability following simultaneous administration of a 130‐mg evacetrapib oral dose and 4‐h intravenous (IV) infusion of 175 µg [(13)C(8)]‐evacetrapib as a tracer. Plasma samples collected through 168 h were...

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Detalhes bibliográficos
Publicado no:J Labelled Comp Radiopharm
Main Authors: Cannady, Ellen A., Aburub, Aktham, Ward, Chris, Hinds, Chris, Czeskis, Boris, Ruterbories, Kenneth, Suico, Jeffrey G., Royalty, Jane, Ortega, Demetrio, Pack, Brian W., Begum, Syeda L., Annes, William F., Lin, Qun, Small, David S.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Special Issue Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5064742/
https://ncbi.nlm.nih.gov/pubmed/26639670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jlcr.3358
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