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Impact of Increased Gastric pH on the Pharmacokinetics of Evacetrapib in Healthy Subjects
STUDY OBJECTIVE: To examine the effect of increased gastric pH on exposure to evacetrapib, a cholesteryl ester transfer protein inhibitor evaluated for the treatment of atherosclerotic heart disease. DESIGN: Open‐label, two‐treatment, two‐period, fixed‐sequence crossover study. SETTING: Clinical res...
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| Udgivet i: | Pharmacotherapy |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5108428/ https://ncbi.nlm.nih.gov/pubmed/27284735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/phar.1778 |
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