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The efficiency of the translesion synthesis across abasic sites by mitochondrial DNA polymerase is low in mitochondria of 3T3 cells
Translesion synthesis by specialized DNA polymerases is an important strategy for mitigating DNA damage that cannot be otherwise repaired either due to the chemical nature of the lesion. Apurinic/Apyrimidinic (abasic, AP) sites represent a block to both transcription and replication, and are normall...
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| 發表在: | Mitochondrial DNA A DNA Mapp Seq Anal |
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| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4834068/ https://ncbi.nlm.nih.gov/pubmed/26470640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/19401736.2015.1089539 |
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