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Eye irritation testing of nanomaterials using the EpiOcular™ eye irritation test and the bovine corneal opacity and permeability assay

BACKGROUND: Assessment of eye irritation hazard has long been a core requirement in any chemical legislation. Nevertheless, publications focussing on the eye damaging potential of nanomaterials are scarce. Traditionally, eye irritation testing was performed using rabbits. The OECD Test Guideline 437...

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Bibliographic Details
Published in:Part Fibre Toxicol
Main Authors: Kolle, Susanne N., Sauer, Ursula G., Rey Moreno, Maria C., Teubner, Wera, Wohlleben, Wendel, Landsiedel, Robert
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833924/
https://ncbi.nlm.nih.gov/pubmed/27083156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12989-016-0128-6
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