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Eye irritation testing of nanomaterials using the EpiOcular™ eye irritation test and the bovine corneal opacity and permeability assay

BACKGROUND: Assessment of eye irritation hazard has long been a core requirement in any chemical legislation. Nevertheless, publications focussing on the eye damaging potential of nanomaterials are scarce. Traditionally, eye irritation testing was performed using rabbits. The OECD Test Guideline 437...

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Detalhes bibliográficos
Publicado no:Part Fibre Toxicol
Main Authors: Kolle, Susanne N., Sauer, Ursula G., Rey Moreno, Maria C., Teubner, Wera, Wohlleben, Wendel, Landsiedel, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833924/
https://ncbi.nlm.nih.gov/pubmed/27083156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12989-016-0128-6
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