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Eye irritation testing of nanomaterials using the EpiOcular™ eye irritation test and the bovine corneal opacity and permeability assay

BACKGROUND: Assessment of eye irritation hazard has long been a core requirement in any chemical legislation. Nevertheless, publications focussing on the eye damaging potential of nanomaterials are scarce. Traditionally, eye irritation testing was performed using rabbits. The OECD Test Guideline 437...

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Bibliografske podrobnosti
izdano v:Part Fibre Toxicol
Main Authors: Kolle, Susanne N., Sauer, Ursula G., Rey Moreno, Maria C., Teubner, Wera, Wohlleben, Wendel, Landsiedel, Robert
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833924/
https://ncbi.nlm.nih.gov/pubmed/27083156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12989-016-0128-6
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