Whole Brain Radiotherapy and RRx-001: Two Partial Responses in Radioresistant Melanoma Brain Metastases from a Phase I/II Clinical Trial()(): A TITE-CRM Phase I/II Clinical Trial

BACKGROUND: Kim et al. report two patients with melanoma metastases to the brain that responded to treatment with RRx-001 and whole brain radiotherapy (WBRT) without neurologic or systemic toxicity in the context of a phase I/II clinical trial. RRx-001 is an reactive oxygen and reactive nitrogen spe...

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Publicado no:Transl Oncol
Main Authors: Kim, Michelle M., Parmar, Hemant, Cao, Yue, Pramanik, Priyanka, Schipper, Matthew, Hayman, James, Junck, Larry, Mammoser, Aaron, Heth, Jason, Carter, Corey A., Oronsky, Arnold, Knox, Susan J., Caroen, Scott, Oronsky, Bryan, Scicinski, Jan, Lawrence, Theodore S., Lao, Christopher D.
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2016
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Original article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833892/
https://ncbi.nlm.nih.gov/pubmed/27084426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2015.12.003
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