TRLS-07. BRAINSTORM: OUTCOMES FROM A MULTI-INSTITUTIONAL PHASE I/II STUDY OF RRx-001 IN COMBINATION WITH WHOLE BRAIN RADIATION THERAPY FOR PATIENTS WITH BRAIN METASTASES

INTRODUCTION: To determine the recommended Phase II dose of RRx-001, a radiosensitizer with vascular normalizing properties, when used with whole-brain radiation therapy (WBRT) for brain metastases, and to assess whether quantitative changes in perfusion MRI after RRx-001 correlate with response. ME...

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Pubblicato in:Neurooncol Adv
Autori principali: Kim, Michelle, Parmar, Hemant, Schipper, Matthew, Devasia, Theresa, Aryal, Madhava, Kesari, Santosh, O’Day, Steven, Morikawa, Aki, Spratt, Daniel, Junck, Larry, Mammoser, Aaron, Hayman, James, Lawrence, Theodore, Tsien, Christina, Aiken, Robert, Goyal, Sharad, Abrouk, Nacer, Trimble, Malcolm, Cao, Yue, Lao, Christopher
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
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Abstracts
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7213090/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdz014.040
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