RING finger protein 31 promotes p53 degradation in breast cancer cells

The atypical E3 ubiquitin ligase RNF31 is highly expressed in human breast cancer, the most frequent neoplastic lethality among women. Here, RNF31 depletion in breast cancer cells in combination with global gene expression profiling revealed p53 (TP53) signaling as a potential RNF31 target. Interest...

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Detalles Bibliográficos
Publicado en:Oncogene
Main Authors: Zhu, J, Zhao, C, Zhuang, T, Jonsson, P, Sinha, I, Williams, C, Strömblad, S, Dahlman-Wright, K
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833873/
https://ncbi.nlm.nih.gov/pubmed/26148235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.260
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