The atypical ubiquitin ligase RNF31 stabilizes estrogen receptor α and modulates estrogen-stimulated breast cancer cell proliferation

Estrogen receptor α (ERα) is initially expressed in the majority of breast cancers and promotes estrogen-dependent cancer progression by regulating the transcription of genes linked to cell proliferation. ERα status is of clinical importance, as ERα-positive breast cancers can be successfully treate...

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Bibliographische Detailangaben
Hauptverfasser: Zhu, J, Zhao, C, Kharman-Biz, A, Zhuang, T, Jonsson, P, Liang, N, Williams, C, Lin, C-Y, Qiao, Y, Zendehdel, K, Strömblad, S, Treuter, E, Dahlman-Wright, K
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2014
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4141304/
https://ncbi.nlm.nih.gov/pubmed/24441041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.573
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