RING finger protein 31 promotes p53 degradation in breast cancer cells

The atypical E3 ubiquitin ligase RNF31 is highly expressed in human breast cancer, the most frequent neoplastic lethality among women. Here, RNF31 depletion in breast cancer cells in combination with global gene expression profiling revealed p53 (TP53) signaling as a potential RNF31 target. Interest...

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Bibliografiske detaljer
Udgivet i:Oncogene
Main Authors: Zhu, J, Zhao, C, Zhuang, T, Jonsson, P, Sinha, I, Williams, C, Strömblad, S, Dahlman-Wright, K
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833873/
https://ncbi.nlm.nih.gov/pubmed/26148235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.260
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