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Cooperative Clustering Digitizes Biochemical Signaling and Enhances its Fidelity

Many membrane-bound molecules in cells form small clusters. It has been hypothesized that these clusters convert an analog extracellular signal into a digital intracellular signal and that this conversion increases signaling fidelity. However, the mechanism by which clusters digitize a signal and th...

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Dades bibliogràfiques
Publicat a:Biophys J
Autors principals: Roob, Edward, Trendel, Nicola, Rein ten Wolde, Pieter, Mugler, Andrew
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833775/
https://ncbi.nlm.nih.gov/pubmed/27074690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.02.031
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