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Cooperative Clustering Digitizes Biochemical Signaling and Enhances its Fidelity

Many membrane-bound molecules in cells form small clusters. It has been hypothesized that these clusters convert an analog extracellular signal into a digital intracellular signal and that this conversion increases signaling fidelity. However, the mechanism by which clusters digitize a signal and th...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biophys J
Prif Awduron: Roob, Edward, Trendel, Nicola, Rein ten Wolde, Pieter, Mugler, Andrew
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Biophysical Society 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833775/
https://ncbi.nlm.nih.gov/pubmed/27074690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.02.031
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