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Salmeterol enhances the cardiac response to gene therapy in Pompe disease

Enzyme replacement therapy (ERT) with recombinant human (rh) acid α-glucosidase (GAA) has prolonged the survival of patients. However, the paucity of cation-independent mannose-6-phosphate receptor (CI-MPR) in skeletal muscle, where it is needed to take up rhGAA, correlated with a poor response to E...

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Detalles Bibliográficos
Publicado en:Mol Genet Metab
Main Authors: Han, Sang-oh, Li, Songtao, Koeberl, Dwight D.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833676/
https://ncbi.nlm.nih.gov/pubmed/27017193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2016.03.006
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