6β-HYDROXYTESTOSTERONE, A CYTOCHROME P450 1B1-TESTOSTERONE-METABOLITE, MEDIATES ANGIOTENSIN II-INDUCED RENAL DYSFUNCTION IN MALE MICE

6β-hydroxytestosterone, a cytochrome P450 1B1-derived metabolite of testosterone, contributes to the development of angiotensin II-induced hypertension and associated cardiovascular pathophysiology. In view of the critical role of angiotensin II in the maintenance of renal homeostasis, development o...

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Detalhes bibliográficos
Publicado no:Hypertension
Main Authors: Pingili, Ajeeth K., Thirunavukkarasu, Shyamala, Kara, Mehmet, Brand, David, Katsurada, Akemi, Majid, Dewan S. A., Navar, L. Gabriel, Gonzalez, Frank J., Malik, Kafait U.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833582/
https://ncbi.nlm.nih.gov/pubmed/26928804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.115.06936
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