Genomic Characterization of Esophageal Squamous Cell Carcinoma Reveals Critical Genes Underlying Tumorigenesis and Poor Prognosis

The genetic mechanisms underlying the poor prognosis of esophageal squamous cell carcinoma (ESCC) are not well understood. Here, we report somatic mutations found in ESCC from sequencing 10 whole-genome and 57 whole-exome matched tumor-normal sample pairs. Among the identified genes, we characterize...

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Publicat a:Am J Hum Genet
Autors principals: Qin, Hai-De, Liao, Xiao-Yu, Chen, Yuan-Bin, Huang, Shao-Yi, Xue, Wen-Qiong, Li, Fang-Fang, Ge, Xiao-Song, Liu, De-Qing, Cai, Qiuyin, Long, Jirong, Li, Xi-Zhao, Hu, Ye-Zhu, Zhang, Shao-Dan, Zhang, Lan-Jun, Lehrman, Benjamin, Scott, Alan F., Lin, Dongxin, Zeng, Yi-Xin, Shugart, Yin Yao, Jia, Wei-Hua
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833434/
https://ncbi.nlm.nih.gov/pubmed/27058444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2016.02.021
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