Genomic Characterization of Esophageal Squamous Cell Carcinoma Reveals Critical Genes Underlying Tumorigenesis and Poor Prognosis

The genetic mechanisms underlying the poor prognosis of esophageal squamous cell carcinoma (ESCC) are not well understood. Here, we report somatic mutations found in ESCC from sequencing 10 whole-genome and 57 whole-exome matched tumor-normal sample pairs. Among the identified genes, we characterize...

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Опубликовано в: :Am J Hum Genet
Главные авторы: Qin, Hai-De, Liao, Xiao-Yu, Chen, Yuan-Bin, Huang, Shao-Yi, Xue, Wen-Qiong, Li, Fang-Fang, Ge, Xiao-Song, Liu, De-Qing, Cai, Qiuyin, Long, Jirong, Li, Xi-Zhao, Hu, Ye-Zhu, Zhang, Shao-Dan, Zhang, Lan-Jun, Lehrman, Benjamin, Scott, Alan F., Lin, Dongxin, Zeng, Yi-Xin, Shugart, Yin Yao, Jia, Wei-Hua
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2016
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833434/
https://ncbi.nlm.nih.gov/pubmed/27058444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2016.02.021
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