Caenorhabditis elegans PAQR-2 and IGLR-2 Protect against Glucose Toxicity by Modulating Membrane Lipid Composition

In spite of the worldwide impact of diabetes on human health, the mechanisms behind glucose toxicity remain elusive. Here we show that C. elegans mutants lacking paqr-2, the worm homolog of the adiponectin receptors AdipoR1/2, or its newly identified functional partner iglr-2, are glucose intolerant...

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Publicado en:PLoS Genet
Autores principales: Svensk, Emma, Devkota, Ranjan, Ståhlman, Marcus, Ranji, Parmida, Rauthan, Manish, Magnusson, Fredrik, Hammarsten, Sofia, Johansson, Maja, Borén, Jan, Pilon, Marc
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2016
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833288/
https://ncbi.nlm.nih.gov/pubmed/27082444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005982
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