Caenorhabditis elegans PAQR-2 and IGLR-2 Protect against Glucose Toxicity by Modulating Membrane Lipid Composition

In spite of the worldwide impact of diabetes on human health, the mechanisms behind glucose toxicity remain elusive. Here we show that C. elegans mutants lacking paqr-2, the worm homolog of the adiponectin receptors AdipoR1/2, or its newly identified functional partner iglr-2, are glucose intolerant...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Svensk, Emma, Devkota, Ranjan, Ståhlman, Marcus, Ranji, Parmida, Rauthan, Manish, Magnusson, Fredrik, Hammarsten, Sofia, Johansson, Maja, Borén, Jan, Pilon, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833288/
https://ncbi.nlm.nih.gov/pubmed/27082444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005982
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados