Regulation of normal B-cell differentiation and malignant B-cell survival by OCT2

The requirement for the B-cell transcription factor OCT2 (octamer-binding protein 2, encoded by Pou2f2) in germinal center B cells has proved controversial. Here, we report that germinal center B cells are formed normally after depletion of OCT2 in a conditional knockout mouse, but their proliferati...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Hodson, Daniel J., Shaffer, Arthur L., Xiao, Wenming, Wright, George W., Schmitz, Roland, Phelan, James D., Yang, Yandan, Webster, Daniel E., Rui, Lixin, Kohlhammer, Holger, Nakagawa, Masao, Waldmann, Thomas A., Staudt, Louis M.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2016
Matèries:
PNAS Plus
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833274/
https://ncbi.nlm.nih.gov/pubmed/26993806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1600557113
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