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Trastuzumab improves tumor perfusion and vascular delivery of cytotoxic therapy in a murine model of HER2+ breast cancer: preliminary results

To employ in vivo imaging and histological techniques to identify and quantify vascular changes early in the course of treatment with trastuzumab in a murine model of HER2+ breast cancer. Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) was used to quantitatively characterize vessel pe...

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Foilsithe in:Breast Cancer Res Treat
Main Authors: Sorace, Anna G., Quarles, C. Chad, Whisenant, Jennifer G., Hanker, Ariella B., McIntyre, J. Oliver, Sanchez, Violeta M., Yankeelov, Thomas E.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833210/
https://ncbi.nlm.nih.gov/pubmed/26791520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-016-3680-8
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