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Identifying 24 h variation in the pharmacokinetics of levofloxacin: a population pharmacokinetic approach

AIM: The objective of this study was to investigate whether the pharmacokinetics of orally administered levofloxacin show 24 h variation. Levofloxacin was used as a model compound for solubility and permeability independent absorption and passive renal elimination. METHODS: In this single centre, cr...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Kervezee, Laura, Stevens, Jasper, Birkhoff, Willem, Kamerling, Ingrid M. C., de Boer, Theo, Dröge, Melloney, Meijer, Johanna H., Burggraaf, Jacobus
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833164/
https://ncbi.nlm.nih.gov/pubmed/26852745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12783
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