The effect of food and formulation on the population pharmacokinetics of cholesteryl ester transferase protein inhibitor DRL‐17822 in healthy male volunteers

We aimed to characterise the population pharmacokinetics of cholesteryl ester transferase protein inhibitor DRL‐17822 in healthy males and explore the effect of food and formulation on the oral absorption of DRL‐17822 in 4 phase I studies. DRL‐17822 was dosed orally (2–1000 mg) in 2 different drug f...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Goulooze, Sebastiaan C., Kruithof, Annelieke C., Alikunju, Shanavas, Gautam, Anirudh, Burggraaf, Jacobus, Kamerling, Ingrid M.C., Stevens, Jasper
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Short Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7495284/
https://ncbi.nlm.nih.gov/pubmed/32250455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.14297
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