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A Coevolutionary Arms Race between Hosts and Viruses Drives Polymorphism and Polygenicity of NK Cell Receptors

Natural killer cell receptors (NKRs) monitor the expression of major histocompatibility class I (MHC-I) and stress molecules to detect unhealthy tissue, such as infected or tumor cells. The NKR gene family shows a remarkable genetic diversity, containing several genes encoding receptors with activat...

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Bibliografiske detaljer
Udgivet i:Mol Biol Evol
Main Authors: Carrillo-Bustamante, Paola, Keşmir, Can, de Boer, Rob J.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833080/
https://ncbi.nlm.nih.gov/pubmed/25911231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msv096
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