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Specificity of inhibitory KIRs enables NK cells to detect changes in an altered peptide environment
The activity of natural killer (NK) cells is tightly regulated by inhibitory and activating receptors. Inhibitory killer immunoglobulin-like receptors (iKIRs) survey the surface of target cells by monitoring the expression of human leukocyte antigen (HLA) class I. The binding of iKIRs has been shown...
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| Publicado no: | Immunogenetics |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5775373/ https://ncbi.nlm.nih.gov/pubmed/28695292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00251-017-1019-1 |
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