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Principles for predicting RNA secondary structure design difficulty

Designing RNAs that form specific secondary structures is enabling better understanding and control of living systems through RNA-guided silencing, genome editing and protein organization. Little is known, however, about which RNA secondary structures might be tractable for downstream sequence desig...

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Bibliographische Detailangaben
Veröffentlicht in:J Mol Biol
Hauptverfasser: Anderson-Lee, Jeff, Fisker, Eli, Kosaraju, Vineet, Wu, Michelle, Kong, Justin, Lee, Jeehyung, Lee, Minjae, Zada, Mathew, Treuille, Adrien, Das, Rhiju
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833017/
https://ncbi.nlm.nih.gov/pubmed/26902426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2015.11.013
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