Extracellular Matrix Mediated Maturation of Human Pluripotent Stem Cell Derived Cardiac Monolayer Structure and Electrophysiological Function

BACKGROUND: Human pluripotent stem cell-derived cardiomyocyte (hPSC-CMs) monolayers generated to date display an immature embryonic-like functional and structural phenotype that limits their utility for research and cardiac regeneration. In particular, the electrophysiological function of hPSC-CM mo...

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Detalhes bibliográficos
Publicado no:Circ Arrhythm Electrophysiol
Main Authors: Herron, Todd J., Rocha, Andre Monteiro Da, Campbell, Katherine, Ponce-Balbuena, Daniela, Willis, B. Cicero, Guerrero-Serna, Guadalupe, Liu, Qinghua, Klos, Matt, Musa, Hassan, Zarzoso, Manuel, Bizy, Alexandra, Furness, Jamie, Anumonwo, Justus, Mironov, Sergey, Jalife, José
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833010/
https://ncbi.nlm.nih.gov/pubmed/27069088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCEP.113.003638
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