Inhibition of Platelet-Derived Growth Factor-AB Signaling Prevents Electromechanical Remodeling of Adult Atrial Myocytes that Contact Myofibroblasts

BACKGROUND: Persistent atrial fibrillation (PAF) results in electromechanical and structural remodeling by mechanisms that are poorly understood. Myofibroblast proliferation and fibrosis is a major source of structural remodeling in PAF. Myofibroblasts also interact with atrial myocytes via direct p...

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Main Authors: Musa, Hassan, Kaur, Kuljeet, O’Connell, Ryan, Klos, Matt, Guerrero-Serna, Guadalupe, Avula, Uma Mahesh R, Herron, Todd J., Kalifa, Jerômé, Anumonwo, Justus MB, Jalife, José
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3692578/
https://ncbi.nlm.nih.gov/pubmed/23499624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hrthm.2013.03.014
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