Simultaneous Voltage and Calcium Mapping of Genetically Purified Human iPS Cell-Derived Cardiac Myocyte Monolayers

RATIONALE: Human induced pluripotent stem cell derived cardiomyocytes (iPSC-CMs) offer a powerful in-vitro tool to investigate disease mechanisms and to perform patient-specific drug screening. To date electrophysiological analysis of iPSC-CMs has been limited to single cell recordings or low resolu...

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Main Authors: Lee, Peter, Klos, Matt, Bollensdorff, Christian, Hou, Luqia, Ewart, Paul, Kamp, Timothy J., Zhang, Jianhua, Bizy, Alexandra, Guerrero-Serna, Guadalupe, Kohl, Peter, Jalife, José, Herron, Todd J.
Format: Artigo
Jezik:Inglês
Izdano: 2012
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423450/
https://ncbi.nlm.nih.gov/pubmed/22570367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.111.262535
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