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Exome‐wide single‐base substitutions in tissues and derived cell lines of the constitutive Fhit knockout mouse
Loss of expression of Fhit, a tumor suppressor and genome caretaker, occurs in preneoplastic lesions during development of many human cancers. Furthermore, Fhit‐deficient mouse models are exquisitely susceptible to carcinogen induction of cancers of the lung and forestomach. Due to absence of Fhit g...
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| Publicado no: | Cancer Sci |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4832848/ https://ncbi.nlm.nih.gov/pubmed/26782170 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12887 |
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