Galectin-1 drives lymphoma CD20 immunotherapy resistance: validation of a preclinical system to identify resistance mechanisms

Non-Hodgkin lymphoma (NHL) is the most commonly diagnosed hematologic cancer of adults in the United States, with the vast majority of NHLs deriving from malignant B lymphocytes that express cell surface CD20. CD20 immunotherapy (rituximab) is widely used to treat NHL, even though the initial effect...

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Vydáno v:Blood
Hlavní autoři: Lykken, Jacquelyn M., Horikawa, Mayuka, Minard-Colin, Veronique, Kamata, Masahiro, Miyagaki, Tomomitsu, Poe, Jonathan C., Tedder, Thomas F.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2016
Témata:
Immunobiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832507/
https://ncbi.nlm.nih.gov/pubmed/26888257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-11-681130
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