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Regulatory B cell production of IL-10 inhibits lymphoma depletion during CD20 immunotherapy in mice

Current therapies for non-Hodgkin lymphoma commonly include CD20 mAb to deplete tumor cells. However, the response is not durable in a substantial proportion of patients. Herein, we report our studies in mice testing the hypothesis that heterogeneity in endogenous tissue CD20(+) B cell depletion inf...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Horikawa, Mayuka, Minard-Colin, Veronique, Matsushita, Takashi, Tedder, Thomas F.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Clinical Investigation 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204847/
https://ncbi.nlm.nih.gov/pubmed/22019587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI59266
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